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Human P2RY1 Stable Cell Line-1321N1 astrocytoma

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Cat.No.
CSC-RG0912
Background
The human P2Y family of metabotropic receptors include eight accepted members, including P2Y1,2,4,6,11,12,13,14. P2Y2,4,11 are activated mainly by nucleoside triphosphates whereas P2Y1,6,12,13 are activated by nucleoside diphosphates. P2Y1 couples preferentially to Gq/11 and is expressed in a variety of tissues including platelets, endothelia, smooth muscle, CNS, osteoblasts and B-islet cells.
Growth Properties
Adherent
Morphology
Glial
Host Cell
1321N1 astrocytoma
Stability
12 passages (6 weeks of continuous culture)
Ship
Dry ice
Gene Information
Official Symbol
P2RY1
Synonyms
P2RY1; purinergic receptor P2Y, G-protein coupled, 1; P2Y purinoceptor 1; P2Y1; ATP receptor; platelet ADP receptor; P2 purinoceptor subtype Y1;
Gene ID
MIM
UniProt ID
P47900
Chromosome Location
3q25.2
Pathway
ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Hemostasis, organism-specific biosystem;
Function
A1 adenosine receptor binding; ADP binding; ATP binding; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; protein heterodimerization activity; receptor activity; signal transducer activity;

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