Human KISS1R Stable Cell Line-CHO dhfr-

Name: Human KISS1R Stable Cell Line-CHO dhfr-
SKU: CSC-RG0278
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0278

Host Cell : CHO dhfr- Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0278
Background	The Kisspeptin receptor KiSS1 is also known as metastin receptor or GPR54. Kisspeptin is a metastasis suppressor protein that suppresses metastasis in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The KiSS1 receptor is involved in thyroid cancer, esophageal squamous cell carcinoma and hepatocellular carcinoma.
Target Gene	KISS1R
Gene Species	Homo sapiens (Human)
Abbr	CHO dhfr--HuKISS1R
Alias	KISS1R, AXOR12, GPR54, HOT7T175, KISS-1R
Host Cell	CHO dhfr-
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	KISS1R KISS1 receptor [ Homo sapiens ]
Gene Symbol	KISS1R
Synonyms	KISS1R; AXOR12; GPR54; HOT7T175; KISS-1R; KISS1 receptor; G protein-coupled receptor 54; G-protein coupled receptor OT7T175; hypogonadotropin-1; kiSS-1 receptor; kisspeptins receptor; metastin receptor
GeneID	84634
Uni ProtID	Q969F8
Chromosome Location	19p13.3
Function	neuropeptide binding; neuropeptide receptor activity; protein binding
Pathway	Class A/1 (Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; Gastrin-CREB signalling pathway via PKC and MAPK; Neuroactive ligand-receptor interaction; Peptide ligand-binding receptors;
MIM	604161

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