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Human KISS1R Stable Cell Line-CHO dhfr-

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Cat.No.
CSC-RG0278
Background
The Kisspeptin receptor KiSS1 is also known as metastin receptor or GPR54. Kisspeptin is a metastasis suppressor protein that suppresses metastasis in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The KiSS1 receptor is involved in thyroid cancer, esophageal squamous cell carcinoma and hepatocellular carcinoma.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO dhfr-
Ship
Dry ice
Gene Information
Official Symbol
KISS1R
Synonyms
KISS1R; AXOR12; GPR54; HOT7T175; KISS-1R; KISS1 receptor; G protein-coupled receptor 54; G-protein coupled receptor OT7T175; hypogonadotropin-1; kiSS-1 receptor; kisspeptins receptor; metastin receptor
Gene ID
MIM
UniProt ID
Q969F8
Chromosome Location
19p13.3
Pathway
Class A/1 (Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; Gastrin-CREB signalling pathway via PKC and MAPK; Neuroactive ligand-receptor interaction; Peptide ligand-binding receptors;
Function
neuropeptide binding; neuropeptide receptor activity; protein binding

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