Panoply™ Human KISS1R Knockdown Stable Cell Line

Name: Panoply™ Human KISS1R Knockdown Stable Cell Line
SKU: CSC-DC008233
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC008233

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC008233
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	KISS1R
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	KISS1R KISS1 receptor [ Homo sapiens ]
Gene Symbol	KISS1R
Synonyms	KISS1R; AXOR12; GPR54; HOT7T175; KISS-1R; KISS1 receptor; G protein-coupled receptor 54; G-protein coupled receptor OT7T175; hypogonadotropin-1; kiSS-1 receptor; kisspeptins receptor; metastin receptor
GeneID	84634
Uni ProtID	Q969F8
Chromosome Location	19p13.3
Function	neuropeptide binding; neuropeptide receptor activity; protein binding
Pathway	Class A/1 (Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; Gastrin-CREB signalling pathway via PKC and MAPK; Neuroactive ligand-receptor interaction; Peptide ligand-binding receptors;
MIM	604161

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