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Human KCNQ2/KCNQ3 Stable Cell Line-HEK293

See other products for KCNQ3
Cat.No.
CSC-RI0145
Background
The human KCNQ2 and KCNQ3 genes encode the pore-forming subunits of Kv7.2 and Kv7.3, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive neuronal activity. Mutations in KCNQ2 or KCNQ3 that reduce M-current amplitude are responsible for some forms of benign familial neonatal seizure. Kv7.2/Kv7.3 channels are therapeutic targets in seizure, stroke, migraine, dementia, bipolar disorder, anxiety, and neuropathic pain.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
KCNQ3
Synonyms
KCNQ3; potassium voltage-gated channel, KQT-like subfamily, member 3; EBN2; potassium voltage-gated channel subfamily KQT member 3; Kv7.3; potassium channel subunit alpha KvLQT3; voltage-gated potassium channel subunit Kv7.3; potassium channel, voltage-gated, subfamily Q, member 3; BFNC2; KV7.3; FLJ37386; FLJ38392; DKFZp686C0248;
Gene ID
MIM
UniProt ID
O43525
Chromosome Location
8q24
Pathway
Axon guidance, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem;
Function
potassium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity;
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Cat#
Product Name
Titer
Product Size
Species
Price
AD08458Z
>1x 10^9 vp/ml
1 x 0.2 ml
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