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Rat Kcnq3 cDNA Clone(NM_031597.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012753

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Gene Information

Cat. No. CDFR012753
Description NativeORF clone of Rattus norvegicus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3) as transfection-ready DNA NM_031597.3
Product Type cDAN Clone
Gene Abbr Kcnq3
Species Rat
Vector pCMV6Entry
Target Gene KCNQ3
Background This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
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