Human KCNN4 Stable Cell Line-CHO

See other products for KCNN4

Cat.No.

CSC-RI0112

Background

The human KCNN4 gene encodes the pore-forming subunit of KCa3.1, the calcium-activated IK potassium channel. KCa3.1 channels expressed in lymphocytes, fibroblasts, proliferating vascular smooth muscle cells, vascular endothelium and, intestinal and airway epithelia are therapeutic targets in inflammatory diseases in these tissues. KCa3.1 channels expressed in erthrocytes have been investigated as targets for treatment of sickle cell anemia.

Growth Properties

Adherent

Morphology

Epithelial-like

Host Cell

CHO-K1

Ship

Dry ice

Gene Information

Gene Name

KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 [ Homo sapiens ]

Official Symbol

KCNN4

Synonyms

KCNN4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; intermediate conductance calcium-activated potassium channel protein 4; hIKCa1; hKCa4; hSK4; KCa3.1; SKCa4; SKCa 4; putative Gardos channel; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; IK1; SK4; KCA4; IKCA1;

Gene ID

3783

MIM

602754

UniProt ID

O15554

Chromosome Location

19q13.2

Pathway

Ca2+ activated K+ channels, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem;

Function

calcium-activated potassium channel activity; calmodulin binding; ion channel activity; protein phosphatase binding; small conductance calcium-activated potassium channel activity;

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Gene Symbol

Species

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CSC-SC007998

Panoply™ Human KCNN4 Over-expressing Stable Cell Line

HEK293 ,CHO, etc.

KCNN4

Human