Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CSC-RI0031
Host Cell : CHO-K1 Size : >1x106 frozen cells/vial
| Cat. No. | CSC-RI0031 |
| Description | This cell line is engineered to overexpress human KCNA6. |
| Background | Kv1.6 is expressed in the brain (astrocytes, oligodendrocytes), colon, germ cells, heart, lung and pulmonary artery smooth muscle cells. This ion channel is involved with the maintenance of the resting membrane potential and therefore regulates the activity of excitable cells. |
| Target Gene | KCNA6 |
| Gene Species | Homo sapiens (Human) |
| Abbr | CHO-HuKCNA6 |
| Alias | KCNA6, HBK2, Kv1.6, KV1.6, FLJ25134 |
| Host Cell | CHO-K1 |
| Host Cell Species | Cricetulus griseus (Chinese hamster) |
| Applications |
1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Channelopathies research |
| Size | >1x106 frozen cells/vial |
| Stability | Validated for at least 10 passages |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Storage | Liquid nitrogen |
| Shipping | Dry ice |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Growth Properties | Adherent |
| Morphology | Epithelial-like |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
| Gene Name | KCNA6 potassium voltage-gated channel, shaker-related subfamily, member 6 [ Homo sapiens ] |
| Gene Symbol | KCNA6 |
| Synonyms | KCNA6; potassium voltage-gated channel, shaker-related subfamily, member 6; potassium voltage-gated channel subfamily A member 6; HBK2; Kv1.6; human brain potassium channel-2; voltage-gated potassium channel HBK2; voltage-gated potassium channel protein Kv1.6; voltage-gated potassium channel subunit Kv1.6; KV1.6; FLJ25134; |
| GeneID | 3742 |
| Uni ProtID | P17658 |
| mRNA Refseq | BC069355 |
| Chromosome Location | 12p13 |
| Function | voltage-gated ion channel activity; voltage-gated potassium channel activity; |
| Pathway | Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem; |
| MIM | 176257 |
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