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Human KCNN3 Stable Cell Line-CHO

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Cat.No.
CSC-RI0110
Background
The human KCNN3 gene encodes the pore-forming subunit of KCa2.3, the calcium-activated, voltage-gated SK3 potassium channel. KCa2 channels are responsible for afterhyperpolarization that regulates neuronal repetitive excitation. KCa2.3 channels expressed in CNS neurons are therapeutic targets in neurologic disorders (e.g., cognitive impairment and seizure).
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
KCNN3
Synonyms
KCNN3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; small conductance calcium-activated potassium channel protein 3; hSK3; KCa2.3; SKCA3; SKCa 3; SK3;
Gene ID
MIM
UniProt ID
Q9UGI6
Chromosome Location
1q21.3
Pathway
Ca2+ activated K+ channels, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem;
Function
calmodulin binding; ion channel activity; potassium channel activity; small conductance calcium-activated potassium channel activity;

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