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Human KCNJ3/KCNJ5 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0119
Background
The human KCNJ3 and KCNJ5 genes encode the pore-forming subunits of heteromeric Kir3.1/Kir3.4, an inward rectifier potassium channel. Kir3.1/Kir3.4 channels expressed in heart are linked to M2 muscarinic acetylcholine receptors that mediate vagal inhibitory control of heart rate. Kir3.1/Kir3.4 is a potential target for treatment of atrial fibrillation.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
KCNJ5
Synonyms
KCNJ5; potassium inwardly-rectifying channel, subfamily J, member 5; G protein-activated inward rectifier potassium channel 4; CIR; GIRK4; KATP1; Kir3.4; IRK-4; heart KATP channel; inward rectifier K+ channel KIR3.4; cardiac ATP-sensitive potassium channel; LQT13; KIR3.4;
Gene ID
MIM
UniProt ID
P48544
Chromosome Location
11q24
Pathway
Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem;
Function
G-protein activated inward rectifier potassium channel activity; contributes_to inward rectifier potassium channel activity; protein binding; voltage-gated ion channel activity;
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Cat#
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Titer
Product Size
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AD08428Z
>1x 10^9 vp/ml
1 x 0.2 ml
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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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