Human HRH1 Stable Cell Line-CHO-K1

Name: Human HRH1 Stable Cell Line-CHO-K1
SKU: CSC-RG0864
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0864

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0864
Background	Histamine is a ubiquitous messenger that mediates a large number of physiological processes. Its actions are mediated by four receptors named H1, H2, H3 and H4 receptors. The H1 histamine receptor is expressed primarily in lung, vasculature and brain where it mediates smooth muscle contraction, food intake and sleep, amongst other actions. Perhaps most notably, antagonists to this receptor are frequently prescribed to treat respiratory allergies.
Target Gene	HRH1
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuHRH1
Alias	HRH1, H1R, HH1R, H1-R, hisH1
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	HRH1 histamine receptor H1 [ Homo sapiens ]
Gene Symbol	HRH1
Synonyms	H1-R; hisH1
Gene Description	histamine receptor H1
Gene ID	3269
Uni Prot ID	P35367
m RNA Refseq	NM_000861.3
Protein Refseq	NP_000852.1
Chromosome Location	3p25
Function	G-protein coupled receptor activity; histamine binding; histamine receptor activity;
Pathway	Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
MIM	600167

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