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Human CHRNA7 Stable Cell Line-CHO

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Cat.No.
CSC-RI0152
Background
The human CHRNA7 gene encodes the acetylcholine-activated, cationic-selective, nAChRalpha7 channel, expressed in CNS neurons and non-neuronal cells (placenta, endothelia, vascular smooth muscle). The nAChRalpha7 channel is a therapeutic target in treatment of inflammation, schizophrenia, and cognitive impairment.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
CHRNA7
Synonyms
CHRNA7; cholinergic receptor, nicotinic, alpha 7 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 7; neuronal acetylcholine receptor subunit alpha-7; acetylcholine receptor; nicotinic; alpha 7 (neuronal); a7 nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; alpha 7 neuronal nicotinic acetylcholine receptor; acetylcholine receptor, nicotinic, alpha 7 (neuronal); neuronal acetylcholine receptor protein, alpha-7 chain; NACHRA7; CHRNA7-2;
Gene ID
MIM
UniProt ID
P36544
Chromosome Location
15q13.3
Pathway
Acetylcholine Binding And Downstream Events, organism-specific biosystem; Activation of Nicotinic Acetylcholine Receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cholinergic synapse, organism-specific biosystem; Highly calcium permeable postsynaptic nicotinic acetylcholine receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
acetylcholine binding; acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; beta-amyloid binding; chloride channel regulator activity; extracellular ligand-gated ion channel activity; ion channel activity; protein homodimerization activity; receptor activity; toxin binding;

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