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Human P2RX3 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0186
Background
The human P2RX3 gene encodes P2X3, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in spinal cord and sensory neurons. P2X3 receptors are therapeutic targets in treatment of neuropathic and inflammatory pain, inflammatory bowel disease, urinary incontinence, and cough.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
P2RX3
Synonyms
P2RX3; purinergic receptor P2X, ligand-gated ion channel, 3; P2X purinoceptor 3; P2X3; ATP receptor; purinoceptor P2X3; P2X receptor, subunit 3; purinergic receptor P2X3; MGC129956;
Gene ID
MIM
UniProt ID
P56373
Chromosome Location
11q12
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
ATP binding; extracellular ATP-gated cation channel activity; extracellular ATP-gated cation channel activity; ion channel activity; purinergic nucleotide receptor activity; purinergic nucleotide receptor activity; receptor activity;

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