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Human P2RX2/P2RX3 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0184
Background
The human P2RX2 AND P2RX3 genes encode P2X2/P2X3, aheteromeric ionotropic ATP receptor that functions as an ATP-activated cation channel cation channel expressed in CNS and dorsal root ganglion neurons. P2X2/P2X3 receptors expressed in neurons are therapeutic targets in treatment of pain.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
P2RX3
Synonyms
P2RX3; purinergic receptor P2X, ligand-gated ion channel, 3; P2X purinoceptor 3; P2X3; ATP receptor; purinoceptor P2X3; P2X receptor, subunit 3; purinergic receptor P2X3; MGC129956;
Gene ID
MIM
UniProt ID
P56373
Chromosome Location
11q12
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
ATP binding; extracellular ATP-gated cation channel activity; extracellular ATP-gated cation channel activity; ion channel activity; purinergic nucleotide receptor activity; purinergic nucleotide receptor activity; receptor activity;

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