Human AVPR2 Stable Cell Line-CHO-K1

Name: Human AVPR2 Stable Cell Line-CHO-K1
SKU: CSC-RG0939
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0939

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0939
Background	The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b, and V2 receptors. V2 receptors are expressed in kidney where vasopressin exerts its antidiuretic action.
Target Gene	AVPR2
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuAVPR2
Alias	AVPR2, DIR, DIR3, V2R, DI1, DIR, NDI, ADHR, DIR3, MGC126533, MGC138386
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	AVPR2 arginine vasopressin receptor 2 [ Homo sapiens ]
Gene Symbol	AVPR2
Synonyms	DI1; DIR; NDI; V2R; ADHR; DIR3
Gene ID	554
Uni Prot ID	P30518
m RNA Refseq	NM_000054.4
Protein Refseq	NP_000045.1
Chromosome Location	Xq28
Function	vasopressin receptor activity;
Pathway	Aquaporin-mediated transport, organism-specific biosystem; Arf6 trafficking events, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
MIM	300538

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