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Human AVPR1B Stable Cell Line-CHO

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Cat.No.
CSC-RG0937
Background
The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b, and V2 receptors. V1b receptors are expressed in the anterior pituitary where they mediate ACTH release. Selective V1b antagonists have been shown to have anxiolytic and antidepressant effects. This cell line is useful for both radioligand binding and for functional assays.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
At least 6 passages
Ship
Dry ice
Gene Information
Official Symbol
AVPR1B
Synonyms
AVPR1B; arginine vasopressin receptor 1B; AVPR3; vasopressin V1b receptor; V1bR; AVPR V3; AVPR V1b; vasopressin V3 receptor; arginine vasopressin receptor 3; antidiuretic hormone receptor 1B; pituitary vasopressin receptor 3;
Gene ID
MIM
UniProt ID
P47901
Chromosome Location
1q32
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
G-protein coupled receptor activity; peptide hormone binding; protein homodimerization activity; protein kinase C binding; receptor activity; signal transducer activity; vasopressin receptor activity;

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