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Rat Avpr1b ORF Clone(NM_017205.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378270

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Gene Information

Cat. No. CDCR378270
Product Type ORF Clone
Gene Abbr Avpr1b
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1266 bp
Vector pCMV6-Entry
Target Gene AVPR1B
Background The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
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