Panoply™ Human ADRA2B Knockdown Stable Cell Line

Name: Panoply™ Human ADRA2B Knockdown Stable Cell Line
SKU: CSC-DC000331
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000331

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000331
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ADRA2B
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ADRA2B adrenoceptor alpha 2B [ Homo sapiens ]
Gene Symbol	ADRA2B
Synonyms	ADRA2L1; ADRARL1; ADRA2RL1; ALPHA2BAR; alpha-2BAR
Gene Description	adrenergic, alpha-2B-, receptor
Gene ID	151
Uni Prot ID	A2RUS0
m RNA Refseq	NM_000682.5
Protein Refseq	NP_000673.2
Chromosome Location	2q11.1
Function	alpha2-adrenergic receptor activity; epinephrine binding; protein binding;
Pathway	Adrenaline signalling through Alpha-2 adrenergic receptor, organism-specific biosystem; Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (z) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
MIM	104260

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