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shRNA set against Mouse ERBB2 (NM_001003817.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH286809

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Gene Information

Cat. No. SHH286809
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ERBB2
Gene Name Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Mus musculus ]
Gene Symbol Erbb2
Synonyms Neu; HER2; HER-2; c-neu; Erbb-2; c-erbB2; mKIAA3023
Gene Description v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Gene ID 13866
Uni Prot ID A2A557
m RNA Refseq NM_001003817.1
Protein Refseq NP_001003817.1
Chromosome Location 11 D; 11 57.0 cM
Function ATP binding; Hsp90 protein binding; RNA polymerase I core binding; glycoprotein binding; identical protein binding; kinase activity; nucleotide binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein kinase activity; protein phosphatase binding; protein tyrosine kinase activity; receptor signaling protein tyrosine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups; transmembrane receptor protein tyrosine kinase activity; transmembrane signaling receptor activity; ubiquitin protein ligase binding;
Pathway Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem;
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