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shRNA set against Human LIG4 (NM_002312.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH330251

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Gene Information

Cat. No. SHH330251
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr LIG4
Gene Name LIG4 ligase IV, DNA, ATP-dependent [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name LIG4 ligase IV, DNA, ATP-dependent [ Homo sapiens ]
Gene Symbol LIG4
Gene Description ligase IV, DNA, ATP-dependent
Gene ID 3981
Uni Prot ID P49917
m RNA Refseq NM_002312.3
Protein Refseq NP_002303.2
Chromosome Location 13q33-q34
Function ATP binding; DNA binding; DNA ligase (ATP) activity; DNA ligase activity; DNA ligase activity; ligase activity; metal ion binding; protein C-terminus binding; protein binding;
Pathway 2-LTR circle formation, organism-specific biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Early Phase of HIV Life Cycle, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem;
MIM 601837
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