Mouse Erbb2 HEK293 Cell Lysate

Name: Mouse Erbb2 HEK293 Cell Lysate
SKU: CLOE-2501
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2501 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2501
Introduction	This cell lysate over-expresses mouse Erbb2 (P70424) (Met 1-Thr 653) fused with C-terminal his tag. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Erbb2
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Mus musculus ]
Gene Symbol	Erbb2
Synonyms	Neu; HER2; HER-2; c-neu; Erbb-2; c-erbB2; mKIAA3023
Gene Description	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Gene ID	13866
Uni Prot ID	A2A557
m RNA Refseq	NM_001003817.1
Protein Refseq	NP_001003817.1
Chromosome Location	11 D; 11 57.0 cM
Function	ATP binding; Hsp90 protein binding; RNA polymerase I core binding; glycoprotein binding; identical protein binding; kinase activity; nucleotide binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein kinase activity; protein phosphatase binding; protein tyrosine kinase activity; receptor signaling protein tyrosine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups; transmembrane receptor protein tyrosine kinase activity; transmembrane signaling receptor activity; ubiquitin protein ligase binding;
Pathway	Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem;

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