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RABV-CVS-ENVA-ΔG-mCherry-2a-Cre

For research use only. Not intended for any clinical use.

Cat. No. :   VNTR-9

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Virus Particles Information

Cat. No. VNTR-9
Description CVS-N2c rabies virus strain-based retrograde monosynaptic tracer with G gene deleted and EnvA-pseudotyped, co-expressing mCherry and Cre recombinase via a self-cleaving 2A peptide. After monosynaptic retrograde spread, presynaptic neurons express mCherry (for visualization) and Cre (for activating Cre-dependent reporters/effectors in postsynaptic targets), enabling input-specific targeting with the full Cre toolbox.
Product Type Rabies virus
Reporter mCherry + Cre recombinase (2A self-cleaving)
Synaptic Transmission Mono-synaptic (with TVA + N2c-G/RV-G helper AAV)
Applications
  1. Retrograde monosynaptic tracing combined with Cre-mediated targeting of presynaptic neurons
  2. Activation of Cre-dependent reporters, optogenetic effectors, or calcium indicators in monosynaptic input neurons
  3. Intersectional targeting of inputs and projection-defined subpopulations
  4. Long-term circuit dissection with reduced toxicity from the CVS-N2c backbone.
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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