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rAAV-CaMKIIa-N2cG

For research use only. Not intended for any clinical use.

Cat. No. :   RABVH-48

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Virus Particles Information

Cat. No. RABVH-48
Description Constitutive AAV helper expressing the CVS-N2c glycoprotein (N2cG) under CaMKIIa, targeting excitatory neurons. N2cG complements G-deleted rabies virus with greater transsynaptic efficiency and lower neuronal toxicity than standard RVG, allowing efficient single-step retrograde input mapping when co-injected with a TVA-expressing helper.
Product Type Adeno-associated virus
Helper Function AAV helper expressing N2cG in excitatory neurons
Applications
  1. Co-injection with TVA helper AAV and CVS-N2c-EnvA-ΔG RV for monosynaptic retrograde tracing in excitatory neurons
  2. N2cG for higher efficiency and lower toxicity
  3. CaMKIIα restricts to excitatory neurons
  4. Mapping direct presynaptic inputs to excitatory projection neurons with reduced toxicity
Promoter Neuron-specific Promoter
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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