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rAAV-CMV-DIO-oRVG

For research use only. Not intended for any clinical use.

Cat. No. :   RABVH-44

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Virus Particles Information

Cat. No. RABVH-44
Description Cre-dependent AAV helper expressing codon-optimized rabies virus glycoprotein (oRVG) under the strong, broad-spectrum CMV promoter. Cre recombination activates oRVG expression, complementing G-deleted rabies virus and permitting a single retrograde transsynaptic step only from the targeted neurons. The CMV promoter ensures robust glycoprotein levels for efficient monosynaptic tracing with a TVA helper.
Product Type Adeno-associated virus
Expression Mechanism Cre-dependent
Helper Function AAV helper expressing oRVG under Cre-dependent control with broad CMV promoter
Applications
  1. Co-injection with TVA helper AAV and RV-EnvA-ΔG for Cre-dependent monosynaptic retrograde tracing
  2. CMV for broad cellular expression
  3. oRVG for enhanced expression
  4. DIO restricts to Cre+ populations
  5. Mapping direct presynaptic inputs to Cre-defined populations in mixed cellular contexts
Promoter Broad-spectrum Promoter
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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