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rAAV-CAG-FLEX-TVA(E66T)-EGFP

For research use only. Not intended for any clinical use.

Cat. No. :   RABVH-10

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Virus Particles Information

Cat. No. RABVH-10
Description Cre-dependent AAV helper expressing the low-affinity TVA(E66T) receptor fused to EGFP under the CAG promoter in a FLEX switch configuration. Following Cre recombination, these neurons become permissive to EnvA-pseudotyped G-deleted rabies virus while the attenuated receptor suppresses background infection. EGFP marks Cre-positive starter cells for retrograde monosynaptic input mapping.
Product Type Adeno-associated virus
Reporter EGFP
Helper Function AAV helper expressing TVA(E66T) fused with EGFP under Cre-dependent FLEX switch
Applications
  1. Co-injection with RV-EnvA-ΔG for Cre-dependent monosynaptic retrograde tracing
  2. CAG promoter drives strong, broad expression across cell types
  3. TVA(E66T) reduces background starter cell artifacts
  4. FLEX switch restricts TVA expression to Cre+ populations
  5. Mapping direct presynaptic inputs to Cre-defined populations with high signal intensity
Promoter Broad-spectrum Promoter
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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