MALT1 Activity Assay Kit

Name: MALT1 Activity Assay Kit
SKU: PTAK-027

For research use only. Not intended for any clinical use.

Cat.No.

PTAK-027

Description

The MALT1 Activity Assay Kit is designed to measure MALT1 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.

Applications

Great for studying enzyme kinetics and HTS applications.

Caution

Avoid freeze/thaw cycles

Component

•Active MALT1 enzyme
•MALT1 fluorogenic substrate
•MALT1 assay buffer
•DTT
•Microtiter plate

Method

Fluorescence

Size/Form

100 assays

Publications

Q & A

Customer Reviews

Customer Q&As

What is MALT1?

A: MALT1 stands for Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1. It is a protein that plays a crucial role in immune system signaling and regulation.

What is the structure of MALT1?

A: MALT1 has an N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (Bcl10) protein and a caspase-like domain.

What is the role of MALT1 in cellular processes?

A: MALT1 acts as a protease, cleaving other proteins to activate signaling pathways involved in inflammation, immune responses, and cell survival. It is particularly important in the development and function of B cells.

What diseases are MALT1 associated with?

A: MALT1 mutations or dysregulation have been associated with various diseases, including lymphomas and autoimmune disorders.

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