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PTAK-027

MALT1 Activity Assay Kit

For research use only. Not intended for any clinical use.

Cat. No. :   PTAK-027

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Product Information

Cat. No. PTAK-027
Description The MALT1 Activity Assay Kit is designed to measure MALT1 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.
Component •Active MALT1 enzyme
•MALT1 fluorogenic substrate
•MALT1 assay buffer
•DTT
•Microtiter plate
Applications Great for studying enzyme kinetics and HTS applications.
Size 100 assays
Method Fluorescence
Caution Avoid freeze/thaw cycles
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What is MALT1?

A: MALT1 stands for Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1. It is a protein that plays a crucial role in immune system signaling and regulation.

What is the structure of MALT1?

A: MALT1 has an N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (Bcl10) protein and a caspase-like domain.

What is the role of MALT1 in cellular processes?

A: MALT1 acts as a protease, cleaving other proteins to activate signaling pathways involved in inflammation, immune responses, and cell survival. It is particularly important in the development and function of B cells.

What diseases are MALT1 associated with?

A: MALT1 mutations or dysregulation have been associated with various diseases, including lymphomas and autoimmune disorders.

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