Factor XIIa Activity Assay Kit

Name: Factor XIIa Activity Assay Kit
SKU: PTAK-035
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : PTAK-035

Inquire for Price

Product Information

Cat. No.	PTAK-035
Description	The Factor XIIa Activity Assay Kit utilizes the ability of factor XIIa to cleave a synthetic substrate to release p-Nitroaniline (pNA) which can be quantitatively measured by a colorimetric assay (OD405 nm). The kit is easy-to-use and can detect Factor XIIa (as low as 1 mPEU) from plasma sampless.
Component	•FXIIa Assay Buffer •FXIIa Activator •FXIIa Substrate •Human Factor XIIa •FXIIa Inhibitor •pNA Standard
Applications	Useful for detecting the activity of Factor XIIa.
Size	100 assays
Method	Colorimetric
Caution	Avoid freeze/thaw cycles

Quick Inquiry

Q & A

Customer Reviews

Customer Q&As

What is Factor XIIa?

A: Factor XIIa is a serine protease that plays a critical role in the intrinsic pathway of blood coagulation. It is the activated form of coagulation Factor XII (FXII).

What is the size of Factor XIIa?

A: The size of Factor XIIa (activated Factor XII) is approximately 80 kilodaltons (kDa).

What is the role of Factor XIIa in hereditary angioedema (HAE)?

A: In some individuals with HAE, Factor XIIa has been found to be overactive, leading to excessive activation of the bradykinin pathway. Blockade or inhibition of Factor XIIa has shown promising results in attenuating the symptoms of HAE.

What is the role of Factor XIIa in blood coagulation?

A: Factor XIIa helps activate Factor XI, which in turn activates Factor IX. Factor IX then activates Factor X, leading to the formation of thrombin and the conversion of fibrinogen into fibrin. Fibrin forms a meshwork that stabilizes the blood clot.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *