Cathepsin E Activitu Assay

Name: Cathepsin E Activitu Assay
SKU: PTAK-016
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : PTAK-016

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Product Information

Cat. No.	PTAK-016
Description	The Cathepsin E Activity Assay Kit utilizes the ability of Cathepsin E to cleave a synthetic MCA-based peptide substrate to release free MCA, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin E-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the MCA fluorescence.
Component	•Cathepsin E •CTSE substrate •Cathepsin assay buffer •CTSE inhibitor
Applications	Useful for detecting the activity of Cathepsin E and screening/characterizing the potential inhibitors of Cathepsin E.
Size	100 assays
Method	Fluorescence
Caution	Avoid freeze/thaw cycles

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What is cathepsin E?

A: Cathepsin E is a type of enzyme belonging to the cathepsin family.

Where is cathepsin E primarily expressed?

A: Cathepsin E is mainly found in intracellular compartments such as endosomes and lysosomes.

What is the role of cathepsin E in cellular processes?

A: Cathepsin E is involved in the degradation of proteins and peptides within the cell, playing a role in cellular processes such as antigen presentation, protein turnover, and digestion.

What diseases are cathepsin E associated with?

A: A deficiency in the levels of Cathepsin E in the body may play a part in inflammatory skin diseases such as atopic dermatitis, for which treatment would rely on fixing functionality and levels of the protein in the body.

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