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Cathepsin E Activitu Assay

For research use only. Not intended for any clinical use.
Cat.No.
PTAK-016
Description
The Cathepsin E Activity Assay Kit utilizes the ability of Cathepsin E to cleave a synthetic MCA-based peptide substrate to release free MCA, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin E-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the MCA fluorescence.
Applications
Useful for detecting the activity of Cathepsin E and screening/characterizing the potential inhibitors of Cathepsin E.
Caution
Avoid freeze/thaw cycles
Component
•Cathepsin E
•CTSE substrate
•Cathepsin assay buffer
•CTSE inhibitor
Method
Fluorescence
Size/Form
100 assays

Publications

Q & A

Customer Reviews

Customer Q&As
What is cathepsin E?

A: Cathepsin E is a type of enzyme belonging to the cathepsin family.

Where is cathepsin E primarily expressed?

A: Cathepsin E is mainly found in intracellular compartments such as endosomes and lysosomes.

What is the role of cathepsin E in cellular processes?

A: Cathepsin E is involved in the degradation of proteins and peptides within the cell, playing a role in cellular processes such as antigen presentation, protein turnover, and digestion.

What diseases are cathepsin E associated with?

A: A deficiency in the levels of Cathepsin E in the body may play a part in inflammatory skin diseases such as atopic dermatitis, for which treatment would rely on fixing functionality and levels of the protein in the body.

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