MMP-1 Activity Assay Kit

Name: MMP-1 Activity Assay Kit
SKU: PTAK-039

For research use only. Not intended for any clinical use.

Cat.No.

PTAK-039

Description

MMP-1 (interstitial collagenase, fibroblast collagenase) is an extracellular protease. This enzyme plays a significant role in cancer, arthritis and other diseases, and has been identified as a drug-screening target. The MMP-1 Assay Kit is designed to measure MMP-1 activity for screening and profiling applications based on fluorescence resonance energy transfer (FRET) using a labeled peptide substrate

Applications

Useful for detecting the activity of MMP-1 and screening the MMP-1 inhibitor.

Caution

Avoid freeze/thaw cycles

Component

•MMP-1 assay buffer
•MMP-1 substrate
•MMP-1 enzyme
•APMA

Method

Fluorescence

Size/Form

100 assays

Publications

Q & A

Customer Reviews

Customer Q&As

What is MMP-1?

A: MMP-1 stands for Matrix Metalloproteinase-1, which is an enzyme found in many tissues and cells in the body.

What is the structure of MMP-1?

A: MMP-1 has an archetypal structure consisting of a pre-domain, a pro-domain, a catalytic domain, a linker region and a hemopexin-like domain.

What is the role of MMP-1 in physiological and pathological processes?

A: MMP-1 plays a role in various physiological and pathological processes, including wound healing, tissue remodeling, inflammatory responses, and cancer metastasis.

What diseases are MMP-1 associated with?

A: Dysregulation of MMP-1 activity has been associated with various diseases, such as arthritis, fibrosis, and cardiovascular disorders.

What is the size of the MMP-1?

A: MMP-1 has an estimated molecular mass of 54 kDa.

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