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Human TREM2 Stable Cell Line - k562

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-SC016549-1

Host Cell :   K562 Size :   >1x106 frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No. CSC-SC016549-1
Description This cell line is engineered to stably express human triggering receptor expressed on myeloid cells 2 (TREM2) in K562 cells.
Target Gene TREM2
Gene Species Homo sapiens (Human)
Host Cell K562
Host Cell Species Homo sapiens (Human)
Applications

1. Studying the interactions between immune cells and cancer cells

2. Studying the mechanisms of resistance to immune checkpoint blockade

3. High-throughput screening

4. Drug target validation

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens ]
Gene Symbol TREM2
Synonyms TREM-2; Trem2a; Trem2b; Trem2c
GeneID 54209
Uni ProtID Q5TCX1
mRNA Refseq NM_018965.2
Protein Refseq NP_061838.1
Chromosome Location 6p21.1
Function receptor activity;
Pathway Axon guidance, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem;
MIM 605086
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Easy to Use

After using the product, the K562 cell line is easier to cultivate and expand, quickly and in large quantities, and the operation is simple.

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