Human LAG3 Stable Cell Line - 3A9

Name: Human LAG3 Stable Cell Line - 3A9
SKU: CSC-RO0941
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RO0941

Host Cell : 3A9 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RO0941
Description	This cell line is engineered to stably overexpress human LAG3.
Target Gene	LAG3
Gene Species	Homo sapiens (Human)
Host Cell	3A9
Host Cell Species	Mus musculus (Mouse)
Applications	1. Studying the interactions between immune cells and cancer cells 2. Studying the mechanisms of resistance to immune checkpoint blockade 3. High-throughput screening 4. Drug target validation
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	LAG3 lymphocyte-activation gene 3 [ Homo sapiens ]
Gene Symbol	LAG3
Synonyms	CD223
Gene Description	lymphocyte-activation gene 3
GeneID	3902
Uni ProtID	P18627
mRNA Refseq	NM_002286.5
Protein Refseq	NP_002277.4
Chromosome Location	12p13.32
Function	MHC class II protein binding; antigen binding; transmembrane signaling receptor activity;
MIM	153337

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Q & A

Customer Reviews

Customer Q&As

Has Human LAG3 Stable Cell Line - 3A9 been used in other scientific research?

A: Human LAG3 Stable Cell Line - 3A9 is a mature and stable cell line that has been widely used and has achieved good experimental results.

Is the LAG3 expressed in Human LAG3 Stable Cell Line - 3A9 an immune protein?

A: LAG-3 (Lymphocyte Activation Gene-3, also known as CD223) is an inhibitory immune checkpoint protein. Like PD-1 and CTLA-4, LAG-3 is not expressed on naive T cells, but its expression can be induced on CD4+ and CD8+ T cells upon antigen stimulation, inhibiting T cell function.

Is Human LAG3 Stable Cell Line - 3A9 a human cell?

A: The 3A9 cells used are mouse cells.

Does Human LAG3 Stable Cell Line - 3A9 provide a related safety data sheet (MSDS) for the cell line?

A: You can inquire with customer service on the official product website.

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