DPP3 Activity Assay Kit

Name: DPP3 Activity Assay Kit
SKU: PTAK-021

For research use only. Not intended for any clinical use.

Cat.No.

PTAK-021

Description

The DPP3 Assay Kit is designed to measure DPP3 activity using purified DPP3 for screening or profiling applications. The key to the DPP3 Assay Kit is the specific, fluorogenic substrate. Using this kit, only one simple step on a microtiter plate is required for DPP3 reactions; no time-consuming washing steps are required. The fluorometric substrate is incubated with a sample containing DPP3 enzyme to produce a fluorophore that can then be measured using a fluorescence reader.

Applications

Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Caution

Avoid freeze/thaw cycles

Component

•Active DPP3
•DPP3 fluorogenic substrate
•DPP3 assay buffer
•Fluorogenic AMC standard
•Microtiter plate

Method

Fluorescence

Size/Form

100 assays

Publications

Q & A

Customer Reviews

Customer Q&As

What is DPP3?

A: Dipeptidyl peptidase 3 (DPP3) is an enzyme that belongs to the family of serine peptidases.

Where is DPP3 mainly expressed?

A: DPP3 is primarily expressed in the cytoplasm of various tissues, including the heart, kidney, liver, and skeletal muscle.

What is the function of DPP3?

A: DPP3 plays a role in the regulation of cellular metabolism and is involved in the breakdown of peptides. It cleaves dipeptides from the N-terminus of proteins, specifically preferring substrates with proline in the second position.

What diseases is DPP3 related to?

A: Research has shown that DPP3 is overexpressed in certain types of cancer, such as ovarian and lung cancer, indicating its potential as a therapeutic target. In addition, it has been suggested that DPP3 may have a role in heart failure, as its expression levels have been found to be elevated in patients with the condition.

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