Rat Cnr2 Stable Cell Line-CHO-K1

Name: Rat Cnr2 Stable Cell Line-CHO-K1
SKU: CSC-RG0815
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0815

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0815
Background	The CB2 cannabinoid receptor is expressed primarily in cells of the peripheral immune system and is a target for cannabinoids (Munro et al., 1993; Gerard et al., 1991), the psychoactive ingredients of marijuana. Other members of the cannabinoid family of receptors include the CB1 cannabinoid receptor, which is expressed primarily in brain, and GPR55 (Ryberg, 2007). When activated, the CB2 receptor inhibits adenylate cyclase by coupling through Gi.
Target Gene	Cnr2
Abbr	CHO-RatCnr2
Alias	CNR2, CB-2, rCB2, CB2
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	Cnr2 cannabinoid receptor 2 (macrophage) [ Mus musculus ]
Gene Symbol	Cnr2
Synonyms	CB2; CB-2; CB2-R
Gene Description	cannabinoid receptor 2 (macrophage)
GeneID	12802
Uni ProtID	P47936
mRNA Refseq	NM_009924.3
Protein Refseq	NP_034054.3
Chromosome Location	4 D3; 4
Function	G-protein coupled receptor activity; cannabinoid receptor activity; signal transducer activity;
Pathway	Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;

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