Human S1PR1-tGFP Stable Cell Line-HepG2

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Cat.No.

CSC-RG0027

Background

This gene encodes S1P1 receptor which is a member of the G protein-coupled receptor superfamily (S1P1-5) originally known as EDG receptors. Through the interaction with this receptor family, sphingosine-1-phosphate stimulates diverse cellular responses, including cytoskeletal changes, proliferation and migration. The S1P1R is widely expressed including on endothelial cells. The physiological effects of S1P1R have been described in immune and vascular systems

Growth Properties

Adherent

Morphology

Epithelial

Host Cell

HepG2

Ship

Dry ice

Gene Information

Gene Name

S1PR1 sphingosine-1-phosphate receptor 1 [ Homo sapiens ]

Official Symbol

S1PR1

Synonyms

S1PR1; sphingosine-1-phosphate receptor 1; EDG1, endothelial differentiation, sphingolipid G protein coupled receptor, 1; sphingosine 1-phosphate receptor 1; CD363; D1S3362; edg 1; S1P receptor 1; S1P receptor Edg-1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; FLJ58121;

Gene ID

1901

MIM

601974

UniProt ID

P21453

Chromosome Location

1p21

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Lysosphingolipid and LPA receptors, organism-specific biosystem;

Function

G-protein coupled receptor activity; receptor activity; signal transducer activity; sphingolipid binding; sphingosine-1-phosphate receptor activity;

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