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Human PTGER1 Stable Cell Line-HEK293

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Cat.No.
CSC-RG1641
Background
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
Host Cell
HEK293
Ship
Dry Ice
Antigen Gene Information
Official Symbol
PTGER1
Synonyms
PTGER1; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E2 receptor EP1 subtype; EP1; prostanoid EP1 receptor; PGE receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1, subtype EP1;
GeneID
MIM
UniProt ID
P34995
Chromosome Location
19p13.1
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
G-protein coupled receptor activity; prostaglandin E receptor activity; receptor activity; signal transducer activity;

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