Human P2RY6 Stable Cell Line-1321N1 astrocytoma

Name: Human P2RY6 Stable Cell Line-1321N1 astrocytoma
SKU: CSC-RG0917
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0917

Host Cell : 1321N1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0917
Background	The human P2Y family of metabotropic receptors include eight accepted members, including P2Y1, 2, 4, 6, 11, 12, 13, 14. P2Y2, 4, 11 are activated mainly by nucleoside triphosphates whereas P2Y1, 6, 12, 13 are activated by nucleoside diphosphates. P2Y6 couples preferentially to Gq/11 and is expressed in a variety of tissues including endothelia, smooth muscle, heart, gall-bladder, retina, placenta, spleen.
Target Gene	P2RY6
Gene Species	Homo sapiens (Human)
Abbr	1321N1 astrocytoma-HuP2RY6
Alias	P2RY6, P2Y6, MGC15335
Host Cell	1321N1
Host Cell Species	Homo sapiens (Human)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 [ Homo sapiens ]
Gene Symbol	P2RY6
Synonyms	P2Y6
Gene Description	pyrimidinergic receptor P2Y, G-protein coupled, 6
Gene ID	5031
Uni Prot ID	Q15077
m RNA Refseq	NM_004154.3
Protein Refseq	NP_004145.1
Chromosome Location	11q13.5
Pathway	Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
MIM	602451

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