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Human P2RX7 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0190
Background
The human P2RX7 gene encodes P2X7, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in lymphocytes and microglia. P2X7 receptors are therapeutic targets in treatment of osteoporosis, neuropathic and inflammatory pain, and immune diseases.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
P2RX7
Synonyms
P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; P2X purinoceptor 7; MGC20089; P2X7; ATP receptor; P2Z receptor; P2X7 receptor; purinergic receptor P2X7 variant A;
Gene ID
MIM
UniProt ID
Q99572
Chromosome Location
12q24
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
ATP binding; ATP binding; extracellular ATP-gated cation channel activity; ion channel activity; lipopolysaccharide binding; protein homodimerization activity; purinergic nucleotide receptor activity; receptor activity; receptor binding;

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