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Human NMUR1 Stable Cell Line-CHO-K1

Cat.No.
CSC-RG1689
Host Cell
CHO-K1
Shipping
Dry Ice
Source
CHO-K1
Species
Human
Subgroup
Human
Background
Neuromedin U (NMU) receptors are a group of Gq/11-protein-coupled receptors that are currently divided intotwo subtypes; NMU1 and NMU2. The two subtypes have distinct tissue distributions; NMU1 is expressed in theperiphery (especially in the gastrointestinal tract), whilst NMU2 is expressed in the central nervous system(especially in the substantia nigra, medulla oblongata and pontine reticular formation). NMU receptorsmediate diverse biological effects including contraction of the uterus, peripheral vasoconstriction causinghypertension and activation of the HPA axis resulting in decreased food intake via the CRH system.
Gene Information
Gene Symbol
NMUR1
Synonyms
NMUR1; neuromedin U receptor 1; G protein coupled receptor 66 , GPR66; neuromedin-U receptor 1; FM 3; GPC R; NMU1R; NMU-R1; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; FM3; FM-3; GPC-R; GPR66; (FM-3);
Gene ID
UniProt ID
Q9HB89
mRNA Refseq
BC036543
Chromosome Location
2q37.1
Function
G-protein coupled receptor activity; neuromedin U receptor activity; neuropeptide receptor activity; receptor activity; signal transducer activity;
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
MIM

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