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Human MRGPRX2 Stable Cell Line-CHO-K1

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Cat.No.
CSC-RG1664
Background
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptorfunction and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a highpotency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulationlocomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases inintracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that thisreceptor is G(q)-coupled.
Host Cell
CHO-K1
Ship
Dry Ice
Antigen Gene Information
Official Symbol
MRGPRX2
Synonyms
MRGPRX2; MAS-related GPR, member X2; mas-related G-protein coupled receptor member X2; MRGX2; G protein-coupled receptor MRGX2;
GeneID
MIM
UniProt ID
Q96LB1
Chromosome Location
11p15.1
Function
G-protein coupled receptor activity; neuropeptide binding; receptor activity; signal transducer activity;

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