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Human MRGPRX1 Stable Cell Line-CHO

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Cat.No.
CSC-RG0893
Background
This receptor belongs to a group of 4 sensory neuron-specific G-protein coupled receptors that are expressed solely in small diameter primary sensory neurons. MRGX1 (MAS-related GPR-X1), also known as SNSR4 (sensory neuron-specific G-protein-coupled receptor 4), is potently activated by BAM22 which evokes a large rise in intracellular calcium. Because of their very selective expression pattern in sensory neurons and because these sensory neurons transmit pain, these receptors are of interest as therapeutic targets for the development of pain medications.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
At least 6 passages
Ship
Dry ice
Gene Information
Official Symbol
MRGPRX1
Synonyms
MRGPRX1; MAS-related GPR, member X1; mas-related G-protein coupled receptor member X1; MRGX1; G protein-coupled receptor MRGX1; G protein-coupled receptor SNSR3; sensory neuron-specific G-protein coupled receptor 3/4; GPCR; SNSR4;
Gene ID
MIM
UniProt ID
Q96LB2
Chromosome Location
11p15.1
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity;

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