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Human KCNH2 Stable Cell Line-CHO

See other products for KCNH2
Cat.No.
CSC-RI0136
Background
The human KCNH2 gene encodes the pore-forming subunit of Kv11.1, the voltage-gated hERG potassium channel. HERG channels are upregulated in some types of cancer and may serve as a tumor marker. KCNH2 mutations cause inherited forms of cardiac disorders including both long QT (loss-of-function) and short QT (gain-of-function) syndromes. Inhibition of HERG channels by pharmaceuticals is the primary cause of acquired long QT syndrome and drug-induced torsade de pointe. Therefore, HERG is an anti-target in cardiac risk assessment.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO
Ship
Dry ice
Gene Information
Official Symbol
KCNH2
Synonyms
KCNH2; potassium voltage-gated channel, subfamily H (eag-related), member 2; LQT2; potassium voltage-gated channel subfamily H member 2; erg1; HERG; Kv11.1; ERG-1; H-ERG; hERG-1; eag homolog; eag-related protein 1; ether-a-go-go-related protein 1; ether-a-go-go-related gene potassium channel 1; voltage-gated potassium channel subunit Kv11.1; ether-a-go-go-related potassium channel protein; ERG1; SQT1; HERG1;
Gene ID
MIM
UniProt ID
Q12809
Chromosome Location
7q36.1
Pathway
Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
Function
delayed rectifier potassium channel activity; inward rectifier potassium channel activity; two-component sensor activity; voltage-gated ion channel activity;
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Cat#
Product Name
Titer
Product Size
Species
Price
AD08406Z
>1x 10^9 vp/ml
1 x 0.2 ml
Human

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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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