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Human KCNB1 Stable Cell Line-CHO

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Cat.No.
CSC-RI0035
Background
Kv2.1 is expressed in the brain (cell bodies and dendrites of neurons but not axons, as well as Schwann cells), atria, ventricle, skeletal muscle, cochlea, retina, lung and pulmonary arteries. It is involved in maintaining membrane potential and modulating electrical excitability of both neurons and muscle cells. It is thought that Kv2.1 has a role in the muscle tone of the pulmonary system, as the expression Kv2.1 in pulmonary smooth muscle has been found to be reduced in chronic hypoxic pulmonary hypertension.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
KCNB1
Synonyms
KCNB1; potassium voltage-gated channel, Shab-related subfamily, member 1; potassium voltage-gated channel subfamily B member 1; Kv2.1; h-DRK1 K(+) channel; potassium channel protein DRK1; delayed rectifier potassium channel 1; delayed rectifier potassium channel Kv2.1; voltage-gated potassium channel subunit Kv2.1; DRK1; KV2.1; h-DRK1;
Gene ID
MIM
UniProt ID
Q14721
Chromosome Location
20q13.2
Pathway
Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Regulation of Insulin Secretion by Glucagon-like Peptide-1, organism-specific biosystem;
Function
protein binding; voltage-gated ion channel activity; voltage-gated potassium channel activity;

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