Human KCNA10 Stable Cell Line-CHO-K1

Name: Human KCNA10 Stable Cell Line-CHO-K1
SKU: CSC-RI0033
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RI0033

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RI0033
Description	This cell line is engineered to overexpress human KCNA10.
Background	Kv1.8 is expressed in the adrenal gland, kidney, brain, heart and skeletal muscle. It is involved with the regulation of resting membrane potential and modulating the activity of excitable cells. It has also been shown to modulate the activity of the cells in the renal proximal tubule. Research suggests that Kv1.8 may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential.
Target Gene	KCNA10
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuKCNA10
Alias	KCNA10, Kv1.8, Kcn1
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Channelopathies research
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	KCNA10 potassium voltage-gated channel, shaker-related subfamily, member 10 [ Homo sapiens ]
Gene Symbol	KCNA10
Synonyms	Kcn1; Kv1.8
Gene Description	potassium voltage-gated channel, shaker-related subfamily, member 10
GeneID	3744
Uni ProtID	Q16322
mRNA Refseq	NM_005549.2
Protein Refseq	NP_005540.1
Chromosome Location	1p13.1
Function	intracellular cyclic nucleotide activated cation channel activity; voltage-gated potassium channel activity;
Pathway	Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
MIM	602420

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