Human HTR2C Stable Cell Line-CHO-K1

Name: Human HTR2C Stable Cell Line-CHO-K1
SKU: CSC-RG0783
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0783

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

Inquire for Price

Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0783
Background	Serotonin (5-hydroxytryptamine, 5-HT) exerts its many physiological effects through 13 distinct receptor subtypes in humans. These subtypes fall into seven structurally-defined classes (5HT1 to 5HT7). 5HT2c receptors are expressed in brain and choroid plexus. This receptor has been used as a target for developing drugs to treat migraine and obesity.
Target Gene	HTR2C
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuHTR2C
Alias	HTR2C, HTR1C, 5 HT2C, 5-HT1C, 5-HT-1C, 5-HT-2C, HTR1C, 5-HT2C, 5-HTR2C
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled [ Homo sapiens ]
Gene Symbol	HTR2C
Synonyms	HTR1C; 5-HT2C; 5-HTR2C
Gene Description	5-hydroxytryptamine (serotonin) receptor 2C
GeneID	3358
Uni ProtID	P28335
mRNA Refseq	NM_000868.2
Protein Refseq	NP_000859.1
Chromosome Location	Xq24
Function	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; drug binding; phosphatidylinositol phospholipase C activity; serotonin binding; serotonin receptor activity;
Pathway	Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
MIM	312861

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *