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Human HTR2C Stable Cell Line-CHO

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Cat.No.
CSC-RG0783
Background
Serotonin (5-hydroxytryptamine, 5-HT) exerts its many physiological effects through 13 distinct receptor subtypes in humans. These subtypes fall into seven structurally-defined classes (5HT1 to 5HT7). 5HT2c receptors are expressed in brain and choroid plexus. This receptor has been used as a target for developing drugs to treat migraine and obesity.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
12 passages (6 weeks of continuous culture)
Ship
Dry ice
Gene Information
Official Symbol
HTR2C
Synonyms
HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 2C , HTR1C; 5-hydroxytryptamine receptor 2C; 5 HT2C; 5-HT1C; 5-HT-1C; 5-HT-2C; serotonin receptor 2C; serotonin 5-HT-2C receptor; 5-hydroxytryptamine receptor 1C; HTR1C; 5-HT2C; 5-HTR2C;
Gene ID
MIM
UniProt ID
P28335
Chromosome Location
Xq23
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; G-protein coupled receptor activity; drug binding; phosphatidylinositol phospholipase C activity; receptor activity; serotonin binding; serotonin receptor activity; signal transducer activity;

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