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Human HTR2A Stable Cell Line-U2OS

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Cat.No.
CSC-RG0022
Background
The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors are a group of G protein-coupled receptors
(GPCRs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The
neurotransmitter serotonin acts as their natural ligand. The 5-hydroxytryptamine receptor 2A (5-HT2A) has been involved in diverse psychiatric disorders like schizophrenia, mood disorders, anxiety disorders, obsessive-compulsive disorder, eating disorders, and Alzheimer"s disease.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
U2OS
Ship
Dry ice
Gene Information
Official Symbol
HTR2A
Synonyms
HTR2A; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; 5 hydroxytryptamine (serotonin) receptor 2A , HTR2; 5-hydroxytryptamine receptor 2A; 5 HT2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor; HTR2; 5-HT2A;
Gene ID
MIM
UniProt ID
P28223
Chromosome Location
13q14-q21
Pathway
Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; G-protein coupled receptor activity; drug binding; phosphatidylinositol phospholipase C activity; receptor activity; serotonin binding; serotonin receptor activity; signal transducer activity;

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