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Rat Htr2a ORF Clone(NM_017254.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378318

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Product Information

Gene Information

Cat. No. CDCR378318
Product Type ORF Clone
Gene Abbr Htr2a
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1416 bp
Vector pCMV6-Entry
Target Gene HTR2A
Background This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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