Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR378318
| Cat. No. | CDCR378318 |
| Product Type | ORF Clone |
| Gene Abbr | Htr2a |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 1416 bp |
| Vector | pCMV6-Entry |
| Target Gene | HTR2A |
| Background | This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
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