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Human CHRM5 Stable Cell Line-U2OS

Cat.No.
CSC-RG0015
Abbr
U2OS-HuCHRM5
Alias
CHRM5,HM5
Growth Properties
Adherent
Host Cell
U2OS
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
Muscarinic acetylcholine receptors are G protein-coupled receptors. M1, M3, M5 receptors couple to G proteins of the Gq/11 family, which activate phospholipase C. M2 and M4 receptors couple to Gi/o-type G proteins that inhibit adenylyl cyclase activity. Muscarinic receptors control many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor have not been fully explored; however, stimulation of this receptor is known to effectively decrease cAMP levels and downregulate the activity of protein kinase A (PKA).
For research use only. Not intended for any clinical use.

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