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Human CD27 Stable Cell Line-CHO

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Cat.No.
CSC-RO0066
Cell Line Description
This cell line is a stably transfected cell line which expresses human CD27 molecule without any tag.
Background
CD27 protein is a member of the TNF-receptor superfamily. It is required for generation and long-term maintenance of T cell immunity. This receptor binds to ligand CD70, and plays a crytical role in regulating B-cell activation and immunoglobulin synthesis. It transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Host Cell
CHO-K1
Ship
Dry ice
Antigen Gene Information
Official Symbol
CD27
Synonyms
T14; S152; Tp55; TNFRSF7; S152. LPFS2
GeneID
UniProt ID
P26842
Chromosome Location
12p13.31

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