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Human CD27 Stable Cell Line-CHO

Cat.No.
CSC-RO0066
Description
This cell line is a stably transfected cell line which expresses human CD27 molecule without any tag.
Host Cell
CHO-K1
Shipping
Dry ice
Source
CHO-K1
Species
Human
Target
Human
Background
CD27 protein is a member of the TNF-receptor superfamily. It is required for generation and long-term maintenance of T cell immunity. This receptor binds to ligand CD70, and plays a crytical role in regulating B-cell activation and immunoglobulin synthesis. It transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Gene Information
Gene Symbol
CD27
Synonyms
T14; S152; Tp55; TNFRSF7; S152. LPFS2
Gene ID
UniProt ID
P26842
Chromosome Location
12p13.31

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