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Recombinant Mouse CD27 (C-Fc-6His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00199 Tag :   C-Fc-6His

Expressed Region :   Pro24-Arg182 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00199
Description The Recombinant Mouse CD27 (C-Fc-6His) is produced in our Human Cell expression system. The amino acid region expressed is Pro24-Arg182 with a Fc-6His tag at the C terminus.
Species Mouse
Tag C-Fc-6His
Mol Weight 45.8 KDa
Conjugate Unconjugated
Format Powder
Expressed Region Pro24-Arg182
Expression System Human Cell
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Gene Cd27
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Synonyms CD27 antigen; CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7; CD27
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