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Human C5AR1 Validated Stable Cell Line-CHO

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Cat.No.
CSC-RG1126
Background
C5a receptor (C5a anaphylatoxin chemotactic receptor, or CD88 antigen, C5R1) is a receptor for chemotactic and inflammatory peptide anaphylatoxin C5a. C5a is a classic, potent inflammatory mediator, and the C5R1 receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. C5a receptor antagonists, such as AcPhe[Orn-Pro-D-cyclohexylalanine-Trp-Arg], show therapeutic effects in various inflammatory disease models. C5a receptor may also be involved in neurodegeneration and Alzheimer"s disease.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
C5AR1
Synonyms
C5AR1; complement component 5a receptor 1; C5R1, complement component 5 receptor 1 (C5a ligand); C5a anaphylatoxin chemotactic receptor; C5A; C5AR; CD88; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1; C5R1;
Gene ID
MIM
UniProt ID
P21730
Chromosome Location
19q13.3-q13.4
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;
Function
C5a anaphylatoxin receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity;
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Cat#
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Titer
Product Size
Species
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AD02636Z
>1x 10^9 vp/ml
1 x 0.2 ml
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CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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