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Human AVPR1A Stable Cell Line-CHO

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Cat.No.
CSC-RG0936
Background
The pituitary hormone vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes the V1a, V1b, and V2 receptors. V1a receptors have been shown to be expressed in vascular smooth muscle, hepatocytes, various blood cells, brain, and retina. These receptors mediate cell proliferation, platelet aggregation, coagulation factor release and glycogenolysis. This cell line is useful for both radioligand binding and for functional assays.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
At least 6 passages
Ship
Dry ice
Gene Information
Official Symbol
AVPR1A
Synonyms
AVPR1A; arginine vasopressin receptor 1A; AVPR1; vasopressin V1a receptor; V1aR; AVPR V1a; V1a vasopressin receptor; antidiuretic hormone receptor 1A; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; vascular/hepatic-type arginine vasopressin receptor;
Gene ID
MIM
UniProt ID
P37288
Chromosome Location
12q14-q15
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
G-protein coupled receptor activity; V1A vasopressin receptor binding; peptide hormone binding; protein binding; protein kinase C binding; receptor activity; signal transducer activity; vasopressin receptor activity;

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